Indian Express
6, March 2010
By Jane E Brody
Chennai, India

EXERCISE IS BENEFICIAL FOR CONDITIONS LIKE OSTEOARTHRITIS, FALLS AND HIP FRACTURE, CARDIOVASCULAR DISEASE, RESPIRATORY DISEASES, DIABETES, OSTEOPOROSIS AND OBESITY
Regular exercise is the only well–established fountain of youth –and it is free
A NEW series of studies prompts a review of the myriad benefits to body, mind and longevity of regular physical activity for people of all ages. What,I’d like to know,will persuade the majority of sedentary people to give their bodies the workout they deserve? My hope is that every new testimonial to the value of exercisewillwinafewmoreconvertsuntil everyone is doing it.

In a commentary on the new studies, published in The Archives of Internal Medicine, two geriatricians, Dr Marco Pahor of the University of Florida and Dr Jeff Williamson of Winston–Salem, New Connecticut, pointed to“the power of higher levels of physical activity to aid in the prevention of late–life disability owing to either cognitive impairment or physical impairment.”

They noted that it had long been “well established that higher quantities of physical activity have beneficial effects on numerous age–related conditions such as osteoarthritis, falls and hip fracture, cardiovascular disease, respiratory diseases, cancer, diabetes, osteoporosis and obesity.”

One of the new studies adds mental deterioration, with exercise producing “a significantly reduced risk of cognitive impairment after two years for participants with moderate Sedentary skeptics are fond of saying that of course exercise is associated with good health as one ages; the people who exercise are healthy to begin with. But studies in which some participants are randomly assigned to a physical activity programme and others to a placebo (like simply being advised to exercise) call their bluff.

Even less exacting observational studies, like the Nurses’ Health Study, take into account the well–being of participants at enrollment.

Thus, in one of the new studies, Dr Qi Sun of Harvard School of Public Health and co–authors reported that among the 13,535 nurses who were healthy when they joined the study in 1986, those who reported higher levels of activity in midlife were far more likely to still be healthy a decade or more later at age of 70.

The study found that physical activity increased the nurses’ chances of remaining healthy regardless of body weight, although those who were both lean and active had “the highest odds of successful survival”.

Taking the benefits of exercise one system at a time, here is what recent studieshaveshown,includingseveral published in The Archives of Internal Medicine in December.

Cancer:
In a review last year of 52 studies of exercise and colon cancer, researchers at Washington University School of Medicine in St Louis concluded that people who were most active were 21 per cent lesslikelytodevelopthediseasethan those who were least active, possibly because activity helps to move waste more quickly through the bowel.

The risk of breast cancer, too, is about 16 per cent lower among physically active women, perhaps because exercise reduces tissue exposure to insulin–like growth factor, a known cancer promoter. Indirectly, it may protect postmenopausal women against cancers of endometrium, pancreas, colon and oesophagus and breast cancer, by helping them keep their weight down.

Osteoporosis and Fragility:
Weak bones and muscles increase the risk of falls and fractures . Weight–bearing aerobic activities to increase muscle strength can reduce or even reverse bone loss. In one of the new studies, German researchers who randomly assigned women 65 and older to either an 18–month exercise regimen demonstrated that exercise significantly increased bone density and reduced the risk of falls.

Cardiovascular Disease:
Aerobic exercise has long been established as an invaluable protector of the heart and blood vessels. It increases the heart's ability to work hard, lowers blood pressure and raises blood levels of HDL–cholesterol, which acts as a cleansing agent in arteries. As a result, active individuals of all ages have lower rates of heart attacks and strokes.

Though early studies were conducted only among men, in a 2002 study published in The New England Journal of Medicine, Dr JoAnn E Manson and colleagues found that among 73,743 initially healthy women ages 50 to 79, walking briskly for30minutesadayfivedaysaweek, as well as more vigorous exercise, substantially reduced the risk of heart attacks and other cardiovascu lar events. In another study, women who walked at least one hour a day were 40 per cent less likely to suffer a stroke than women who walked less than an hour a week.

Diabetes:
Moderate activity has been shown to lower the risk of de veloping diabetes even in women of normal weight. A 16–year study of 68,907 initially healthy femalenurses foundthatthosewhoweresedentary t had twice the risk of developing dia l betes, and those who were both – sedentary and obese had 16 times – the risk. Another study that ran – domly assigned 3,234 pre–diabetic men and women to modest physical activity found exercise to be more ef fective than the drug metformin at – preventing full–blown diabetes.

Dementia:
As the population continuestoage,perhapsthegreatest health benefit of regular physical ac, tivity will turn out to be its ability to y prevent or delay the loss of cognitive functions. The new study of 3,485 healthy men and women older than 55 found that those who were physically active three or more times a week, were least likely to become cognitively impaired. One study con : ducted in Australia and published in – September 2008 in The Journal of the r American Medical Association randomly assigned 170 volunteers who k reported memory problems to a sixd month programme of physical activity or health education. A year and a t half later, the exercise group showed – “a modest improvement in cogni f tion”. Various other studies have confirmed the value of exercise in – helping older people maintain use2 ful short–term memory, enabling d them to plan, schedule and multiE task, as well as store information and to use it effectively.