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  • Endocrinology
  • Pancreas

Pancreas

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Pancreas secretes a hormone (insulin) that controls the use of glucose by the body.
Pancreatic Endocrine Hormones and Their Purpose
Insulin
  • Purpose – Regulate blood glucose (sugar) in the normal range (lots more about this).
  • Action – Forces many cells of the body to absorb and use glucose thereby decreasing blood sugar levels.
  • Secreted in response to high blood glucose.
  • Secretion inhibited by low blood glucose.
  • Disease due to deficient action diabetes (large section of Endocrine Web is devoted to Diabetes).
  • Disease due to excess action hypoglycemia.
  • Tumor called Insulinoma.
Glucagon
  • Purpose – Assist insulin in regulating blood glucose (sugar) in the normal range.
  • Action – Forces many cells of the body to release (or produce) glucose (increasing blood sugar).
  • Secreted in response to low blood glucose.
  • Secretion inhibited by high blood glucose.
  • Disease due to deficient action some times nothing, sometimes hypoglycemia.
  • Disease due to excess action hyperglycemia.
  • Tumor called glucagonoma (new page about this soon).
Somatostatin
  • Purpose – Regulate the production and excretion of other endocrine tumors.
  • Action – Slows down production of insulin, glucagon, gastrin, and other endocrine tumors.
  • Secreted in response to high levels of other endocrine hormones.
  • Secretion inhibited by low levels of other endocrine hormones.
  • Disease due to deficient action poorly defined.
  • Disease due to excess action diabetes (inhibits insulin production), gallstones, and dietary fat intolerance.
  • Tumor called somatostatinoma (new page about this soon).
Gastrin
  • Purpose – Assist in digestion within the stomach.
  • Action – Induce acid producing cells of the stomach to produce acid.
  • Secreted in response to food in the stomach and intestines.
  • Secretion inhibited by absence of food in stomach and intestines.
  • Disease due to deficient action poorly defined, some times no symptoms at all.
  • Disease due to excess action stomach ulcers due to excess stomach acid.
  • Tumor called gastrinoma (also called Zollinger Ellison Syndrome) (new page about this soon).
Vasoactive Intestinal Peptide (VIP)
  • Purpose – Help control water secretion and absorption from the intestines.
  • Action – Causes intestinal sells to secrete water and salts into the intestines (inhibit absorption).
  • Secreted in response to unclear.
  • Secretion inhibited by unclear.
  • Disease due to deficient action – No symptoms at all.
  • Disease due to excess action – Severe watery diarrhea and salt (potassium) imbalances.

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Endocrinology

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Health Professional's Negligence
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